How To Re-Warm Previously Fried Fish?
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Cancer: Can we reduce the risk from eating fish?
Cancer. We do our best to avoid talking or even thinking about being a victim. But if something else does not get us first, we are all likely to develop some form of the disease or at least harbor a latent form. Is there something we can do to stack the cards against this?
Genetic Cover
There is no doubt that certain forms of cancer are hereditary. If the children of parents with certain cancers to develop also depends on a unique arrangement of nucleotides, the components associated with specific genes involved in development of the disease. In other words, the same genetic mutation has to be transmitted, too.
Even for those who have undergone a genetic change "with a risk factor significantly higher, recent studies show that there are ways of reorganizing the deck, so to speak.
Common Causes
Researchers from various scientific and medical are demonstrating the importance of inflammation as a cause in the development of a variety of conditions, including heart disease, neurodegenerative diseases like Alzheimer's, type II> type II diabetes, peripheral arterial disease and colon, liver and prostate cancer. Scientific, clinical and epidemiological studies suggest that many diseases are associated with certain lifestyles and, in particular, the types of foods commonly consumed by a population.
These observations recently led a group of researchers to examine more closely the connection between the food we eat, inflammation and disease development, especially prostate cancer. Their results show strong evidence linking an anti-inflammatory nutritional component in risk reduction. (See this issue "Research Update. ")
Inflammation Information
But what, exactly, is inflammation and why that the body has this mechanism, if it contributes to the disease? Here's the short answer:
The cells of the immune system into action at a site the body think you are being attacked by a "bad boy", a pathogen like a virus, bacteria or aberrant cells as a cancer cell. Pathogens anti-immune cells (macrophages) migrate to the tissue involved and immediately activate the biochemical pathways that produce inflammatory molecules and protein (prostaglandins, inflammatory cytokines).
Some of these molecules function as messengers to attract other immune system cells (Neutrophils, mast cells) in the tissue under attack. Defense immune cells start to produce a number of toxic substances (hydrogen peroxide, radicals free superoxide radicals), allegedly led to pathogens.
As with any "weapon of mass destruction" are not only pathogens negatively affected by toxins, but there are also significant collateral damage to normal cells. This is what is known as inflammation: inflammation damages, including the cells genetic material (DNA) and increased permeability of blood vessels, thereby fluid leak in the area.
When inflammation occurs in an exposed part of the body such as the skin appears red and swollen and is often painful. As we age, the inflammatory response becomes even less oriented, representing a high incidence of age-related tissue inflammation.
Omega 3 Protection
Now, back to the study mentioned above and your answer to how it may be possible to prevent a disease associated with reaction Immune system over-exuberant and consequent inflammation.
Prostate cancer accounts for about 30% of cancers in the U.S. The researchers examined the relationship between the incidence of this disease in people and their consumption title = "Omega 3 fatty acids"> omega 3 fatty acids in fish. Subjects who had higher levels of omega-3 plasma were lower incidence of prostate cancer, compared with controls who consumed little or no omega 3-rich fish.
Researchers also found that those with an inherited genetic variation, which usually become more susceptible to aggressive prostate cancer, also responded to omega-3 fatty acids diet. There was a dramatic decrease in the incidence of cancer in these subjects and a significant inhibition of cancer growth preexisting.
Omega 3 Interference
Not only does the research suggest that omega-3 have a protective effect, but the study also identified mechanism.
The previously mentioned gene that confers susceptibility to prostate cancer, codes for an enzyme, COX-2 (COX-2). COX-2 participates in the synthesis of inflammatory mediators, prostaglandins. It appears that the omega-3 fatty acids interfere with this enzyme, preventing conversion omega-6 fatty acids into prostaglandins.
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This study and others suggest the need for a healthy relationship 1:2 of omega 3 to omega 6s in what we eat. The problem? Omega-6 fatty acids are found in many foods prepared with vegetable oils, bread, biscuits, cakes, fried foods are favored in Western diets. The solution may be as simple as substituting olive oil for vegetable oil, whenever possible, including fish meal at least once a week in our diets.
About the Author
Dr. Benjamin Treadwell, Ph.D. is an independent researcher in biochemistry with a life-long interest in metabolism and aging. He previously served as an Associate Professor of Biochemistry at Harvard Medical School and as Director of the Orthopedic Research Laboratory at Massachusetts General Hospital. He earned his Ph.D. in biochemistry at New York University and served as a Research Fellow at the Roche Institute of Molecular Biology in New Jersey.
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